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Wham clusters all of the candidate breakpoints and rounds their positions to the nearest tenth base pair. The placement with the best browse assist is described. If the tender-clipped consensus sequence is usually aligned to your putative breakpoint location utilizing the Smith-Waterman algorithm, the breakpoint is further more refined to The situa
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The delicate-clipped sequences that overhang the breakpoint are collapsed right into a consensus sequence utilizing a a number of sequence alignment (MSA) supplied during the seqAn library [27]. Wham applies three filters towards the consensus sequences. Breakpoints aren't reported in scenarios wherever consensus sequences are shorter than 10 bp or
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